Tag: 100-200

Bayesian separation algorithm of THz spectral sources applied to D-glucose monohydrate dehydration kinetics was written by Sterczewski, L. A.;Grzelczak, M. P.;Nowak, K.;Szlachetko, B.;Plinski, E. F.. And the article was included in Chemical Physics Letters in 2016.Name: (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate This article mentions the following:

An estimation of the dehydration kinetics of monohydrated D-glucose with the use of the Bayesian spectral source separation algorithm is described. The dehydration experiment was probed with the terahertz time domain spectroscopy (THz-TDS). Contrary to the widely used peak-area method, our approach to the quant. anal. takes into account the full spectral information. The obtained concentration profiles at different temperatures were processed in order to measure the kinetics of the dehydration process. Our investigation shows that the proposed method may be used to estimate the evolution of concentration despite the overlapping peaks and multiple spectral sources in the observed spectra. In the experiment, the researchers used many compounds, for example, (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7Name: (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate).

(2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7) belongs to tetrahydropyran derivatives. Dihydropyrans and tetrahydropyrans are examples of cyclic ethers widespread in nature. One classic procedure for the organic synthesis of tetrahydropyran is by hydrogenation of the 3,4-isomer of dihydropyran with Raney nickel.Name: (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Flow Photo-Nazarov Reactions of 2-Furyl Vinyl Ketones: Cyclizing a Class of Traditionally Unreactive Heteroaromatic Enones was written by Ashley, William L.;Timpy, Evan L.;Coombs, Thomas C.. And the article was included in Journal of Organic Chemistry in 2018.Recommanded Product: 5,6-Dihydro-2H-pyran-3-carbaldehyde This article mentions the following:

Nazarov reactions of 2-furyl vinyl ketones and related heteroaromatic enones, to produce furan-fused cyclopentanones using a flow photochem. approach, are described. Compounds possessing this connectivity between heterocycle and ketone (2-furyl, 2-benzofuryl, 2-thiophene-yl, and 2-benzothiophene-yl) have traditionally proven difficult or impossible to cyclize with typical Bronsted and Lewis acid mediated methods. Using mild flow photochem. conditions and acetic acid (AcOH) or hexafluoroisopropanol (HFIP) as solvent, these compounds were found to cyclize in 45-97% yields, with typical UV exposure times of 3.4-6.8 min. In all cases, 2-furyl and 2-thiophene-yl enones cyclized, whereas 2-benzofuryl and 2-benzothiophene-yl enones exhibited divergent properties with reactivity patterns tied to the identity of the vinyl group. This report discloses the first photo-Nazarov reactions of tetrahydropyridine-substituted 2-furyl ketones, providing a direct approach to the corresponding fused heterocyclic motifs built around a central cyclopentanone. These motifs constitute the core structures of biol. active natural products, including the marine alkaloid nakadomarin A. In the experiment, the researchers used many compounds, for example, 5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7Recommanded Product: 5,6-Dihydro-2H-pyran-3-carbaldehyde).

5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7) belongs to tetrahydropyran derivatives. Tetrahydropyrans are also used as important solvents, as chemical intermediate and as monomer for ring-opening polymerization. One classic procedure for the organic synthesis of tetrahydropyran is by hydrogenation of the 3,4-isomer of dihydropyran with Raney nickel.Recommanded Product: 5,6-Dihydro-2H-pyran-3-carbaldehyde

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Carbon-13 NMR spectra of saturated heterocycles. XI. Tetrahydropyrans (oxanes) was written by Eliel, Ernest L.;Manoharan, Muthiah;Pietrusiewicz, K. Michal;Hargrave, Karl D.. And the article was included in Organic Magnetic Resonance in 1983.Reference of 13417-49-7 This article mentions the following:

The ¹³C NMR spectra of 62 oxanes (tetrahydropyrans) with and without Me substituents at various ring positions, some of them bearing in addition (or instead) Et, vinyl, ethynyl, carbomethoxy, and methylol substituents at C-2, have been recorded, and the 294 resulting chem. shifts have been correlated by multiple linear regression anal. Axial and equatorial α-, β-, γ-, δ-, gem– and vic-parameters for shifts caused by Me groups at all ring positions, and similar parameters for the other substituents at C-2, are reported. Standard deviations of the parameters are, in most cases, within 0.3 ppm and the agreement of calculated and exptl. shifts is excellent. ¹³C NMR spectra of a number of addnl. substituted tetrahydropyrans, and of 3,6-dihydro-2H-pyrans and 3,4-dihydro-2H-pyrans, are tabulated and discussed. In the experiment, the researchers used many compounds, for example, 5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7Reference of 13417-49-7).

5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7) belongs to tetrahydropyran derivatives. Numerous natural products have tetrahydropyran skeleton as the building block for designing new natural products and their derivatives e.g. aplysiatoxins, avermectins, oscillatoxins, talaromycins, latrunculins and acutiphycins. One classic procedure for the organic synthesis of tetrahydropyran is by hydrogenation of the 3,4-isomer of dihydropyran with Raney nickel.Reference of 13417-49-7

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Derivatives of 5,6-dihydro-2H-pyran-3-carboxylic acid was written by Spreitzer, Helmut;Mueller, Petra;Buchbauer, Gerhard. And the article was included in Monatshefte fuer Chemie in 1990.Computed Properties of C6H8O2 This article mentions the following:

Some derivatives of 5,6-dihydro-2H-pyran-3-carboxaldehyde (I, R = CHO) and of its oxidation product, 5,6-dihydro-2H-pyran-3-carboxylic acid I (R = CO₂H), were prepared The aldehyde derivatives as well as amides and esters of I (R = CO₂H) were tested in an insecticidal/fungicidal/acaricidal screening program. The Me ester I (R = CO₂Me) shows a distinct knock down effect against the fruit fly Drosophila melanogaster. In the experiment, the researchers used many compounds, for example, 5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7Computed Properties of C6H8O2).

5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7) belongs to tetrahydropyran derivatives. Tetrahydropyran is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and dyestuff. 2-(Arylmethylene)cyclopropylcarbinols could be converted to the corresponding tetrahydropyrans stereoselectively in the presence of Brønsted acids under mild conditions. A plausible Prins-type reaction mechanism has been proposed.Computed Properties of C6H8O2

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

1,2-elimination of alcohol from homoallyl ethers under the influence of mixed metal bases was written by Margot, Christian;Rizzolio, Michele;Schlosser, Manfred. And the article was included in Tetrahedron in 1990.Application of 13417-49-7 This article mentions the following:

Lithium diisopropylamide in the presence of catalytic amounts of potassium tert-butoxide smoothly converts homoallyl or homobenzyl type ethers to dienes or styrenes. γ,δ-Unsaturated acetals give 1,3-dienyl ethers and 4-alkylidenetetrahydropyrans or dihydropyrans produce a variety of dienols. If there is a choice, the new double bond is formed with high trans selectivity while the configuration of existing double bonds is retained. The elimination mode is syn-periplanar and concerted, though E1cb like. In the experiment, the researchers used many compounds, for example, 5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7Application of 13417-49-7).

5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7) belongs to tetrahydropyran derivatives. Tetrahydropyrans are also used as important solvents, as chemical intermediate and as monomer for ring-opening polymerization. The reaction of tertiary 1,4- and 1,5-diols with cerium ammonium nitrate at room temperature gives tetrahydrofuran and tetrahydropyran derivatives in high yield and stereoselectivity. Various fragrant compounds have been synthesized using this method.Application of 13417-49-7

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Gel permeation technique for characterizing chemically modified celluloses was written by Martin, Lawrence F.;Blouin, F. A.;Bertoniere, N. R.;Rowland, S. P.. And the article was included in Tappi in 1969.Quality Control of (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate This article mentions the following:

Gel-permeation chromatog. is an effective method for obtaining quant. phys. measurements of changes produced in the structure of cellulose by chem. modification. The selection of stachyose, raffinose, maltose, and glucose as test solutes resulted in a simple linear relation between elution volume and hydrated mol. weight From this linear relation, extrapolation was made to the effective internal solvent volumes and limits of permeability of the samples. Values obtained were empirical measurements of the permeability of the cellulose samples, and the changes produced by chem. modifications agreed with the alteration of polymer structure. Cellulose crosslinked in the swollen state showed increased permeability because of its larger effective internal volume and limit of permeability. Crosslinking under conditions that minimize swelling increases the internal volume while causing a decrease in the limit of permeability. Monofunctional substitution increases the internal volume to the same extent as crosslinking in an unswollen state while increasing the limit of permeability. Microcrystalline wood cellulose had as large an internal volume as decrystd. cotton cellulose, but a much higher mol.-weight limit of permeability. In the experiment, the researchers used many compounds, for example, (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7Quality Control of (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate).

(2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7) belongs to tetrahydropyran derivatives. Tetrahydropyrans are useful synthons for biologically important compounds. The most notable anticancer agent, bryostatin, and eribulin are marine macrolides having intriguing tetrahydropyran and furan motif. Quality Control of (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Addition of aldehydes to activated double bonds. XXVIII. Preparations and reactions of alkoxy and acetoxy 2,5-diketones was written by Stetter, Hermann;Mohrmann, Karl Heinrich;Schlenker, Walter. And the article was included in Chemische Berichte in 1981.Related Products of 13417-49-7 This article mentions the following:

Reaction of ROCH₂CHO (R = Me, CHMe₂, Bu, CH₂Ph) with R¹COCH:CH₂ (R¹ = Me, Et, Ph) gave ROCH₂COCH₂CH₂COR¹, which were cyclized to I or reacted with R²NH₂ (R² = Me, Ph) to give the pyrroles II. RCOCH₂CH₂COCH₂OAc were obtained from RCHO and CH₂:CHCOCH₂OAc and were deacetylated to RCOCH₂CH₂COCH₂OH. Treatment of CH₂:CHCOR¹ with R³CHO (R³ = 2,3-dihydro-4H-pyran-2-yl, 2,3-dihydro-6H-pyran-2-yl) gave R³COCH₂CH₂COR¹ (R³ = tetrahydropyranyl). In the experiment, the researchers used many compounds, for example, 5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7Related Products of 13417-49-7).

5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7) belongs to tetrahydropyran derivatives. Tetrahydropyrans are also used as important solvents, as chemical intermediate and as monomer for ring-opening polymerization. The bismuth chloride-assisted cross-cyclization between homoallylic alcohols and epoxides provided various benzyl tetrahydropyran derivatives. The reaction afforded good yields of desired products and occurred under mild conditions.Related Products of 13417-49-7

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Use of D-glucose modifications by non-adapted and adapted cell lines was written by Frank, Vladimir;Horakova, Katarina;Valentova, Nadeja;Smelik, Ondrej. And the article was included in Biologia (Bratislava, Slovakia) in 1976.Related Products of 14431-43-7 This article mentions the following:

Three animal cell lines of different origin and different degrees of stabilization (HeLa, LW1, and LWF B55) were cultured in media containing 1 of the following isomers of D-glucose: anhydrous α-D-glucose, β-D-glucose monohydrate, and di-α,β-D-glucose hemihydrate (determined as a racemate). The 3 cell strains exhibited different growth in the 3 different media, and no particular form of glucose was favorable to the growth of all 3 strains, even when the cells were adapted for 7-8 weeks. The cell strains showed different capacities for using the different glucose forms in that they showed different ratios of glucose consumption to growth intensity. Measurements of cell growth, glucose consumption, lactate formation, and glycogen content showed that balanced mixtures of all 3 glucose forms do not lead to identical energy metabolism in the cell cultures used. In the experiment, the researchers used many compounds, for example, (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7Related Products of 14431-43-7).

(2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7) belongs to tetrahydropyran derivatives. Tetrahydropyrans are useful synthons for biologically important compounds. The reaction of tertiary 1,4- and 1,5-diols with cerium ammonium nitrate at room temperature gives tetrahydrofuran and tetrahydropyran derivatives in high yield and stereoselectivity. Various fragrant compounds have been synthesized using this method.Related Products of 14431-43-7

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

1,4-Diazafulvenium salts was written by Behringer, Hans;Tuerck, Ulrich. And the article was included in Chemische Berichte in 1966.COA of Formula: C6H14O7 This article mentions the following:

Solutions of the appropriate I (Ar = Ph or p-MeOC₆H₄, Ar’ = Ph or p-Me₂NC₆H₄) and II (Ar = Ph or p-MeOC₆H₄) in concentrated H₂SO₄ contained the corresponding 6,6-diaryl- and 6-aryl-1,4-diazafulvenium salts. The corresponding 1,4-diazafulvene was isolated in 1 case, namely III by the condensation of the appropriate aryl 2-imidazolyl ketones with Me₂NPh in POCl₃. p-MeOC₆H₄COCH₂Cl (18.5 g.) in 100 cc. hot EtOH treated with 12 cc. AcOH and 13.0 g. NaN₃ in 20 cc. H₂O, stirred 1 hr. at 65-70° and then 4 hrs. at room temperature, refrigerated overnight, and treated with about 40 cc. H₂O yielded 16.0 g. p-MeOC₆H₄COCH₂N₃ (IV), m. 68-71° (Et₂O-petroleum ether). IV (16.0 g.) in 800 cc. C₆H₃Cl₃ heated 45 min. at 200-20°, concentrated, and diluted with cyclohexane gave 8.3 g. V (Ar = p-MeOC₆H₄) (VI), m. 212-15° (aqueous C₅H₅N). p-MeC₆H₄COCH₂Br (64 g.) in 250 cc. EtOH and 35 cc. AcOH stirred 1 day with 39 g. NaN₃ in 60 cc. H₂O and refrigerated 1 week gave 50 g. p-MeC₆H₄COCH₂N₃ (VII), m. 58-60°. VII (13.0 g.) in 900 cc. C₆H₃Cl₃ heated 2 hrs. at 210-20° gave 6.3 g. V (Ar = p-MeC₆H₄), m. 203.5-5.5° (aqueous C₅H₅N). VI (1.54 g.) in 40 cc. POCl₃ treated at 70° under N with 1.25 cc. Me₂NPh, stirred 2 hrs. at 70°, decomposed with iced H₂O, and neutralized with cooling with half-concentrated NH₄OH, and the crude product chromatographed on Al₂O₃ gave 1-5% nearly black III, m. 172.5-3.5° (CH₂Cl₂-cyclohexane-ligroine). III (125 mg.) in 10 cc. C₆H₆ stirred 1 hr. with 0.5 millimoles PhLi-Et₂O yielded VIII, m. 158-61° (aqueous EtOH). The appropriate V (0.01 mole) in dry tetrahydrofuran treated with cooling during 5 min. under N with 21 millimoles suitable aryllithium in Et₂O and kept 20 hrs. at 20° gave the corresponding I. V (Ar = Ph) (IX) yielded 2.50 g. I (Ar = Ar’ = Ph) (X), m. 185-7° (aqueous EtOH). p-Me₂NC₆H₄Li (XI) in Et₂O added to VI in tetrahydrofuran gave 0.95 g. I (Ar = p-MeOC₆H₄, Ar’ = p-Me₂NC₆H₄) (XII), decompose 169-71° (aqueous iso-PrOH). V (Ar = p-MeOC₆H₄) treated successively with 0.01 mole each MeMgI and XI gave a small amount III. XI with IX yielded 0.740 g. gray I (Ar = Ph, Ar’ = p-Me₂NC₆H₄), decompose 166-8° (iso-PrOH-H₂O). X (0.325 g.) dissolved in 8 portions in 1 cc. concentrated H₂SO₄ each, added dropwise with cooling to MeOH, and the combined, pale yellow solution (50 cc.) diluted with 200 cc. H₂O and neutralized with cooling with half-concentrated NH₄OH gave 0.21 g. XIII, m. 134-7° (aqueous EtOH). V (Ar = Ph) (2.48 g.) in 120 cc. AcOH hydrogenated 45 min. over 1 g. Pd-CO yielded 1.57 g. II (Ar = Ph), m. 112-15° (MeNO₂). VI (7.7 g.) in 150 cc. AcOH hydrogenated over 2. g. Pd-C gave 5.5 g. II (Ar = p-MeOC₆H₄), m. 170-2° (MeCN). The uv spectra of III and XII are recorded. In the experiment, the researchers used many compounds, for example, (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7COA of Formula: C6H14O7).

(2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol hydrate (cas: 14431-43-7) belongs to tetrahydropyran derivatives. Tetrahydropyrans and furans principally constitute as a central motif in diverse medicinally privileged molecules. The bismuth chloride-assisted cross-cyclization between homoallylic alcohols and epoxides provided various benzyl tetrahydropyran derivatives. The reaction afforded good yields of desired products and occurred under mild conditions.COA of Formula: C6H14O7

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Iridium-Catalyzed Enantioselective Hydrogenation of Unsaturated Heterocyclic Acids was written by Song, Song;Zhu, Shou-Fei;Pu, Liu-Yang;Zhou, Qi-Lin. And the article was included in Angewandte Chemie, International Edition in 2013.Category: tetrahydropyran This article mentions the following:

A variety of α,β-unsaturated heterocyclic carboxylic acids were hydrogenated with >90% enantiomeric excess using chiral spirophosphine oxazoline iridium complexes. The methodol. was applied the the preparation of γ-aminobutyric acid reuptake inhibitor (R)-tiagabine. In the experiment, the researchers used many compounds, for example, 5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7Category: tetrahydropyran).

5,6-Dihydro-2H-pyran-3-carbaldehyde (cas: 13417-49-7) belongs to tetrahydropyran derivatives. Tetrahydropyrans are useful synthons for biologically important compounds. The most notable anticancer agent, bryostatin, and eribulin are marine macrolides having intriguing tetrahydropyran and furan motif. Category: tetrahydropyran

Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics