Dipole moments and conformation of 3- and 4-bromo- and chloroheteracyclohexanes was written by Remane, H.;Borsdorf, R.;Scholz, M.;Doelle, Erna;Loock, Petra. And the article was included in Journal fuer Praktische Chemie (Leipzig) in 1980.Synthetic Route of C5H9BrO This article mentions the following:
Dipole moments of I (Z = O, S, MeN, CH2; X = Br, Cl) were determined exptl. and calculated by the CNDO/2 and vector addition methods. The dipole moments were used to calculate conformational free energies. The results are discussed in relation to NMR data for I. In the experiment, the researchers used many compounds, for example, 3-Bromo-tetrahydropyran (cas: 13047-01-3Synthetic Route of C5H9BrO).
3-Bromo-tetrahydropyran (cas: 13047-01-3) belongs to tetrahydropyran derivatives. Tetrahydropyrans and furans principally constitute as a central motif in diverse medicinally privileged molecules. The bismuth chloride-assisted cross-cyclization between homoallylic alcohols and epoxides provided various benzyl tetrahydropyran derivatives. The reaction afforded good yields of desired products and occurred under mild conditions.Synthetic Route of C5H9BrO
Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics