Tag: M.W:100-200

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Gold-Catalyzed Domino Cycloisomerization/Alkoxylation: An Entry to 3,4-Dihydro-1H-[1,4]oxazino[4,3-a]indole, published in 2021-12-17, which mentions a compound: 16400-32-1, mainly applied to dihydrooxazinoindole diastereoselective regioselective preparation; alc aldehydeyne domino cycloisomerization alkoxylation gold catalyst, Product Details of 16400-32-1.

A novel and mild synthetic route for the preparation of functionalized polycyclic indole skeletons via a gold-mediated cycloisomerization/alkoxylation of 1,6-aldehyde-yne had been developed. This atom-economical catalytic process that associates IPrAu(MeCN)BF4 and an alc. demonstrated remarkable selectivity in accessing functionalized 3,4-dihydro-1H-[1,4]oxazino[4,3-a]indole derivatives I [R1 = H, Et, Ph, etc.; R2 = H, Me, Br; R3 = H, Cl; R4 = Me, i-Pr, CH2CH=CH2, Bn, CH2CH(CH3)CH2CH3, CH2CH=CCH2CH2CH=C(Me)2] of high synthetic utility (21 examples, yields of ≤96%) and could be optimized under asym. conditions with an enantiomeric excess of ≤86%.

I hope my short article helps more people learn about this compound(1-Bromo-2-pentyne)Product Details of 16400-32-1. Apart from the compound(16400-32-1), you can read my other articles to know other related compounds.

Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: (S)-(2,2-dimethyl-[1,3]-dioxolan-4-yl)-methylamine(SMILESS: NC[C@@H]1OC(C)(C)OC1,cas:82954-65-2) is researched.Related Products of 18362-64-6. The article 《A flexible route to new spirodioxanes, oxathianes, and morpholines》 in relation to this compound, is published in Tetrahedron. Let’s take a look at the latest research on this compound (cas:82954-65-2).

This work describes a modular efficient route to 10-aza-4-thia-, 10-aza-4-oxa-, and 10-oxa-4-thia-1,7-dioxaspiro[5.5]undecanes. The synthetic pathway relies upon the iterative nucleophilic substitution of 1,3-dichloropropan-2-one O-benzyloxime by solketal derivatives The oxime key-intermediates, submitted to an acidic deprotection-spiroacetalization process, afforded these original spiroketal compounds in three steps, few purifications, and very good yields.

I hope my short article helps more people learn about this compound((S)-(2,2-dimethyl-[1,3]-dioxolan-4-yl)-methylamine)Application In Synthesis of (S)-(2,2-dimethyl-[1,3]-dioxolan-4-yl)-methylamine. Apart from the compound(82954-65-2), you can read my other articles to know other related compounds.

Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Formula: C11H13NO2. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: Ethyl indoline-2-carboxylate, is researched, Molecular C11H13NO2, CAS is 50501-07-0, about Convenient synthesis of dioxopiperazines via aminolysis of α-(pyruvylamino) esters. Author is Marshall, J. A.; Schlaf, T. F.; Csernansky, J. G..

Dioxopiperazines I and II were prepared from indoline III by cyclizing with MeNH2 to give dioxopiperazine IV, which was dehydrated to methylene compound V. V added AcSH to give I and II. Analogous reactions starting with pyrrole VI gave dioxopiperazine VII.

I hope my short article helps more people learn about this compound(Ethyl indoline-2-carboxylate)Formula: C11H13NO2. Apart from the compound(50501-07-0), you can read my other articles to know other related compounds.

Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Karuppasamy, Muthu; Vachan, B. S.; Vinoth, Perumal; Muthukrishnan, Isravel; Nagarajan, Subbiah; Ielo, Laura; Pace, Vittorio; Banik, Subrata; Maheswari, C. Uma; Sridharan, Vellaisamy researched the compound: 1-Bromo-2-pentyne( cas:16400-32-1 ).Computed Properties of C5H7Br.They published the article 《Direct Access to 9-Chloro-1H-benzo[b]furo[3,4-e]azepin-1-ones via Palladium(II)-Catalyzed Intramolecular syn-Oxypalladation/Olefin Insertion/sp2-C-H Bond Activation Cascade》 about this compound( cas:16400-32-1 ) in Organic Letters. Keywords: palladium catalyzed cascade synthesis chlorobenzofuroazepinone proparyl arylamine unsaturated ester. We’ll tell you more about this compound (cas:16400-32-1).

An efficient Pd(II)-catalyzed cascade approach was established for the synthesis of 9-chloro-1H-benzo[b]furo[3,4-e]azepin-1-ones starting from N-propargyl arylamines having a pendant α,β-unsaturated ester scaffold. The mechanism of this sequential process involved intramol. syn-oxypalladation followed by olefin insertion and ortho sp2-C-Cl bond formation reactions. This high atom- and step-economical cascade sequence generated two heterocycle rings and three new bonds in a single synthetic operation.

I hope my short article helps more people learn about this compound(1-Bromo-2-pentyne)Computed Properties of C5H7Br. Apart from the compound(16400-32-1), you can read my other articles to know other related compounds.

Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 1-Bromo-2-pentyne(SMILESS: CCC#CCBr,cas:16400-32-1) is researched.Synthetic Route of C6H7NO3. The article 《Synthesis and characterization of nano-zinc wire using a self designed unit galvanic cell in aqueous medium and its reactivity in propargylation of aldehydes》 in relation to this compound, is published in Tetrahedron. Let’s take a look at the latest research on this compound (cas:16400-32-1).

Electrochem. was used for propargylation of carbonyls in aqueous ZnCl2 medium. For electrochem. process the authors designed a unit galvanic cell. ZnCl2 was used as stoichiometric reagent and causes electrochem. deposition of Zn in cathode. Wire shaped nano Zn architecture was formed in cathode during electrochem. process which is the active reagent. Homopropergylic alcs. were synthesized in good yields. After the organic reaction is over aqueous solution containing Zn salts can be reused up to 5th cycle without significant loss of reactivity.

From this literature《Synthesis and characterization of nano-zinc wire using a self designed unit galvanic cell in aqueous medium and its reactivity in propargylation of aldehydes》,we know some information about this compound(16400-32-1)Synthetic Route of C5H7Br, but this is not all information, there are many literatures related to this compound(16400-32-1).

Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called An enantioconvergent halogenophilic nucleophilic substitution (SN2X) reaction, published in 2019-01-25, which mentions a compound: 16400-32-1, mainly applied to nucleophilic substitution enantioselective thiocarboxylate tertiary bromide azide mechanism, Electric Literature of C5H7Br.

Bimol. nucleophilic substitution (SN2) plays a central role in organic chem. In the conventionally accepted mechanism, the nucleophile displaces a carbon-bound leaving group X, often a halogen, by attacking the carbon face opposite the C-X bond. A less common variant, the halogenophilic SN2X reaction, involves initial nucleophilic attack of the X group from the front and as such is less sensitive to backside steric hindrance. Herein, we report an enantioconvergent substitution reaction of activated tertiary bromides by thiocarboxylates or azides that, on the basis of exptl. and computational mechanistic studies, appears to proceed via the unusual SN2X pathway. The proposed electrophilic intermediates, benzoylsulfenyl bromide and bromine azide, were independently synthesized and shown to be effective.

From this literature《An enantioconvergent halogenophilic nucleophilic substitution (SN2X) reaction》,we know some information about this compound(16400-32-1)Electric Literature of C5H7Br, but this is not all information, there are many literatures related to this compound(16400-32-1).

Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 1-Bromo-2-pentyne( cas:16400-32-1 ) is researched.Product Details of 16400-32-1.Yu, Shuling; Hong, Chao; Liu, Zhanxiang; Zhang, Yuhong published the article 《Synthesis of Cyclopentenones through Rhodium-Catalyzed C-H Annulation of Acrylic Acids with Formaldehyde and Malonates》 about this compound( cas:16400-32-1 ) in Organic Letters. Keywords: cyclopentenone preparation alkylation; acrylic acid formaldehyde malonate annulation carbon hydrogen activation. Let’s learn more about this compound (cas:16400-32-1).

An efficient rhodium-catalyzed protocol for the synthesis of cyclopentenones I (R1 = Et, Bn, c-hexyl, etc.; R2 = H, Me, Et, Ph; -R1R2- = -(CH2)3-, -(CH2)4-; R3 = Me, Et, n-Pr, i-Pr, n-Bu) based on a three-component reaction of acrylic acids, formaldehyde, and malonates via vinylic C-H activation is reported. Exploratory studies showed that 5-alkylation of as-prepared cyclopentenones could be realized smoothly by the treatment of a variety of alkyl halides with a Na2CO3/MeOH solution Excess formaldehyde and malonate led to a multicomponent reaction that afforded the multisubstituted cyclopentenones II (R1 = n-Bu, 3-FC6H4, Ph(CH2)2, etc.; R2 = H, Me, Et, etc.; R3 = Me, Et, n-Pr, i-Pr; -R1R2- = -(CH2)4-) through a Michael addition

From this literature《Synthesis of Cyclopentenones through Rhodium-Catalyzed C-H Annulation of Acrylic Acids with Formaldehyde and Malonates》,we know some information about this compound(16400-32-1)Product Details of 16400-32-1, but this is not all information, there are many literatures related to this compound(16400-32-1).

Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 50501-07-0, is researched, SMILESS is O=C(C1NC2=C(C=CC=C2)C1)OCC, Molecular C11H13NO2Journal, Green Chemistry called Reusable, homogeneous water soluble photoredox catalyzed oxidative dehydrogenation of N-heterocycles in a biphasic system: application to the synthesis of biologically active natural products, Author is Srinath, S.; Abinaya, R.; Prasanth, Arun; Mariappan, M.; Sridhar, R.; Baskar, B., the main research direction is pyridoindole preparation green chem; tetrahydropyridoindole oxidative dehydrogenation cobalt phthalocyanine photoredox reusable catalyst; quinoline preparation green chem; tetrahydroquinoline oxidative dehydrogenation cobalt phthalocyanine photoredox reusable catalyst; isoquinoline preparation green chem; tetrahydroisoquinoline oxidative dehydrogenation cobalt phthalocyanine photoredox reusable catalyst; indole preparation green chem; indoline oxidative dehydrogenation cobalt phthalocyanine photoredox reusable catalyst.Application of 50501-07-0.

A simple and efficient method for the oxidative dehydrogenation (ODH) of partially saturated N-heterocycles (indolines, tetrahydro-β-carbolines and tetrahydro(iso)quinolines) e.g., I is described using a reusable, homogeneous cobalt-phthalocyanine photoredox catalyst II (R = SO3Na; M = Co) in a biphasic medium. A biphasic system offers an advantage of easy separation of the product and an efficient reusability of the homogeneous photoredox catalyst. Also, the current system significantly helps to overcome the solubility issue of the substrate and catalyst at room temperature Its potential applications to organic transformations are demonstrated by the synthesis of various biol. active N-heterocycles (indoles, β-carbolines, (iso)quinolines) e.g., III and natural products such as eudistomin U, norharmane, and harmane and precursors to perlolyrine and flazin. Without isolation and purification, the catalyst solution can be reused up to 5 times with almost comparable reactivity. Furthermore, the efficiency of the reaction was demonstrated on a gram scale. To the best of our knowledge, this is the first report on ODH reactions using a non noble, reusable and homogeneous cobalt photoredox catalyst under environmentally friendly conditions.

From this literature《Reusable, homogeneous water soluble photoredox catalyzed oxidative dehydrogenation of N-heterocycles in a biphasic system: application to the synthesis of biologically active natural products》,we know some information about this compound(50501-07-0)Application of 50501-07-0, but this is not all information, there are many literatures related to this compound(50501-07-0).

Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Safety of Ethyl indoline-2-carboxylate. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: Ethyl indoline-2-carboxylate, is researched, Molecular C11H13NO2, CAS is 50501-07-0, about Regiospecific functionalization of indole-2-carboxylates and diastereoselective preparation of the corresponding indolines. Author is Collot, Valerie; Schmitt, Martine; Marwah, Padma; Bourguignon, Jean-Jacques.

The N-acyl derivatives of 3-substituted indole-2-carboxylates prepared through several routes were submitted to catalytic hydrogenation affording either cis- or trans-indoline diastereomers after quant. C-2 epimerization.

From this literature《Regiospecific functionalization of indole-2-carboxylates and diastereoselective preparation of the corresponding indolines》,we know some information about this compound(50501-07-0)Safety of Ethyl indoline-2-carboxylate, but this is not all information, there are many literatures related to this compound(50501-07-0).

Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Microwave induced synthesis of a new class of pyrano isoxazoline and isoxazole annulated chromones – an intramolecular nitrile oxide cycloaddition with tethered olefins and alkynes, published in 2020, which mentions a compound: 16400-32-1, Name is 1-Bromo-2-pentyne, Molecular C5H7Br, Synthetic Route of C5H7Br.

A variety of new highly substituted-tetracyclic pyrano isoxazoline/isoxazole annulated chromone derivatives I [R1 = H, Cl; R2 = H, Me, Ph; R3 = H, Me] and II [R4 = H, Me, Et] were synthesized via eco-friendly microwave assisted/ceric ammonium nitrate (CAN) as an oxidant, intramol. 1,3-dipolar cycloaddition with in situ generated nitrile oxides from aldoximes of alkene/alkyne tethered chromones. This protocol was practically simple and efficient to construct diverse range of substituted pyrano isoxazoline/isoxazole annulated chromone derivatives and gave higher yields of products in microwave irradiation compared to conventional heating. The structures of all the synthesized compounds were established by IR, NMR and mass spectral anal.

From this literature《Microwave induced synthesis of a new class of pyrano isoxazoline and isoxazole annulated chromones – an intramolecular nitrile oxide cycloaddition with tethered olefins and alkynes》,we know some information about this compound(16400-32-1)Synthetic Route of C5H7Br, but this is not all information, there are many literatures related to this compound(16400-32-1).

Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics