Tag: M.W=150-200

Le Pham, Ngoc Son published the artcileOxidative Dehydrosulfurative Cross-Coupling of 3,4-Dihydropyrimidine-2-thiones with Alkynes for Access to 2-Alkynylpyrimidines, HPLC of Formula: 27943-46-0, the publication is Journal of Organic Chemistry (2020), 85(7), 5087-5096, database is CAplus and MEDLINE.

Dihydropyrimidinethiones such as I [R = t-Bu, Me(CH₂)_n, i-PrCH₂CH₂, PhCH₂CH₂, c-C₆H₁₁CH₂, cyclopentyl, cyclohexyl, PhCH₂O(CH₂)₃, THPOCMe₂, Ph, 4-MeC₆H₄, 4-MeOC₆H₄, 1-naphthyl; n = 5, 7; THP = tetrahydro-2-pyranyl] underwent desulfurative Sonogashira coupling and oxidative aromatization reactions with terminal alkynes RCCH in the presence of Pd(OAc)₂, 1,3-bis(diphenylphosphino)propane (dppp), copper(I) 2-thiophenecarboxylate (CuTC), and Cs₂CO₃ in 4:1 toluene:MeCN to yield alkynylpyrimidines such as II [R = t-Bu, Me(CH₂)_n, i-PrCH₂CH₂, PhCH₂CH₂, c-C₆H₁₁CH₂, cyclopentyl, cyclohexyl, PhCH₂O(CH₂)₃, THPOCMe₂, Ph, 4-MeC₆H₄, 4-MeOC₆H₄, 1-naphthyl; n = 5, 7].

Journal of Organic Chemistry published new progress about 27943-46-0. 27943-46-0 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Alkynyl,Ether, name is 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, and the molecular formula is C10H16O2, HPLC of Formula: 27943-46-0.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics

Pimkov, Igor V. published the artcileDesigning the Molybdopterin Core through Regioselective Coupling of Building Blocks, Recommanded Product: 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, the publication is Chemistry – A European Journal (2015), 21(47), 17057-17072, database is CAplus and MEDLINE.

2-Amino-5,6,7,8-tetrahydro-6-[3-hydroxy-1,2-dimercapto-4-(phosphonooxy)-1-buten-1-yl]-4(3H)-pteridinone (i.e. molybdopterin) is an essential cofactor for all forms of life. The cofactor is composed of a pterin moiety appended to a dithiolene-functionalized pyran ring, and through the dithiolene moiety it binds metal ions. Different synthetic strategies for dithiolene-functionalized pyran precursors that have been designed and synthesized are discussed. These precursors also harbor 1,2-diketone or osone (i.e., monosaccharide, osulose) functionality that has been condensed with 1,2-diaminobenzene or other heterocycles resulting in several quinoxaline or pterin derivatives Use of additives improves the regioselectivity of the complexes. The mols. have been characterized by ¹H and ¹³C NMR and IR spectroscopies, as well as by mass spectrometry. In addition, several compounds have been crystallog. characterized. The geometries of the synthesized mols. are more planar than the geometry of the cofactor found in proteins. The synthesis of the target compounds was achieved using 4,4-dimethyl-2-thioxo-4H-1,3-dithiolo[4,5-c]pyran-6,7-dione, 4,4-dimethyl-4H-1,3-dithiolo[4,5-c]pyran-2,6,7-trione as key intermediates. The title compounds thus formed included 4,4-dimethyl-4H-1,3-dithiolo[4,5]pyrano[2,3-b]quinoxaline-2-thione,.

Chemistry – A European Journal published new progress about 27943-46-0. 27943-46-0 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Alkynyl,Ether, name is 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, and the molecular formula is C10H16O2, Recommanded Product: 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics

Sim, So Hee published the artcilePalladium(0)-Catalyzed Decarboxylation of Buta-2,3-dienyl 2′-Alkynoates: Approach to the Synthesis of 2-Alkynyl Buta-1,3-dienes, Application of 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, the publication is Organic Letters (2008), 10(3), 433-436, database is CAplus and MEDLINE.

The Pd(PPh₃)₄-catalyzed decarboxylation of buta-2,3-dienyl 2′-alkynoates allows the rapid construction of 2-alkynyl buta-1,3-dienes, e.g., I. The carbon-carbon bond-forming reaction occurs at the central position of an allene moiety.

Organic Letters published new progress about 27943-46-0. 27943-46-0 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Alkynyl,Ether, name is 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, and the molecular formula is C7H7ClN2, Application of 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics

Hikino, Hiroshi published the artcileSteroids. XXIV. Shidasterone, an insect metamorphosing substance from Blechnum niponicum. Structure, Product Details of C10H16O2, the publication is Chemical & Pharmaceutical Bulletin (1975), 23(7), 1458-79, database is CAplus and MEDLINE.

The structure of shidasterone (I), the phytoecdysone isolated from B. niponicum (Blechnaeceae) was determined Stereoisomers of the cholestane-20,22-diol derivatives were synthesized and their chem. and spectral properties were examined.

Chemical & Pharmaceutical Bulletin published new progress about 27943-46-0. 27943-46-0 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Alkynyl,Ether, name is 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, and the molecular formula is C10H16O2, Product Details of C10H16O2.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics

Torii, Sigeru published the artcileSyntheses of chromones and quinolones via palladium-catalyzed carbonylation of o-iodophenols and anilines in the presence of acetylenes, Synthetic Route of 27943-46-0, the publication is Tetrahedron (1993), 49(31), 6773-84, database is CAplus.

Synthesis of 2-substituted chromones and quinolones has been performed by a Pd-catalyzed carbonylation of o-iodophenols or o-iodoanilines in the presence of terminal acetylenes in a high yield through coupling of halides and acetylenes followed by cyclization as a one-pot reaction.

Tetrahedron published new progress about 27943-46-0. 27943-46-0 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Alkynyl,Ether, name is 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, and the molecular formula is C12H20O6, Synthetic Route of 27943-46-0.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics

Torii, Sigeru published the artcileA facile hydroxymethylation of acetylene derivatives with paraformaldehyde by use of an electrogenerated base (EG base), SDS of cas: 27943-46-0, the publication is Chemistry Letters (1988), 1977-8, database is CAplus.

Electrolysis of a mixture of paraformaldehyde and terminal acetylene derivatives smoothly provided the corresponding hydroxymethylated compounds in high yields by passing less than 1 F/mol of electricity. Electroreduction of paraformaldehyde generated in situ an efficient base (EG base), which catalyzed hydroxymethylation of the acetylenes.

Chemistry Letters published new progress about 27943-46-0. 27943-46-0 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Alkynyl,Ether, name is 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, and the molecular formula is C12H20O6, SDS of cas: 27943-46-0.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics

Torii, Sigeru published the artcilePalladium-catalyzed carbonylation to form 2-substituted 1,4-dihydro-4-oxoquinoline, Formula: C10H16O2, the publication is Tetrahedron Letters (1991), 32(2), 237-40, database is CAplus.

Palladium-catalyzed carbonylation of o-H₂NC₆H₄R (R = Br, I) in the presence of R¹CCH (R¹ = alkyl, cyclohexyl, substituted Ph, benzodioxolyl) under proper conditions (20 kg cm^-2 of CO at 120°) gave a variety of substituted dihydrooxoquinolines I in good yields.

Tetrahedron Letters published new progress about 27943-46-0. 27943-46-0 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Alkynyl,Ether, name is 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, and the molecular formula is C7H13Br, Formula: C10H16O2.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics

Foster, G. L. published the artcileAcetylenic corrosion inhibitors, Synthetic Route of 27943-46-0, the publication is Industrial and Engineering Chemistry (1959), 825-8, database is CAplus.

The mol. of propargyl alc. is systematically substituted and the corrosion inhibition of the resulting compounds is tested on AISI type 1020 mild steel in 10% HCl at 150°F. and in 15% HCl at 175 and 200°F. for 16 hrs., each solution containing 0.4% of the test substance. Of 39 compounds tested only iodopentynol ICCCMe₂OH is a better inhibitor than propargyl alc. The exptl. results confirm the theory that the triple bond is the focal point of the inhibitory action against acid corrosion.

Industrial and Engineering Chemistry published new progress about 27943-46-0. 27943-46-0 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Alkynyl,Ether, name is 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, and the molecular formula is C10H16O2, Synthetic Route of 27943-46-0.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics

Van Snick, Wim published the artcileA facile synthetic route towards substituted thieno[3,2-e]indoles, Recommanded Product: 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, the publication is Synthesis (2009), 767-774, database is CAplus.

A number of substituted thieno[3,2-e]indoles were prepared in high yields via a Bu₄NF-mediated cyclization of 5-acetamido-4-ethynylbenzothiophenes, which, in turn, are easily accessible from the corresponding 4-iodobenzothiophenes. This method presents a viable alternative to the traditionally used Fischer indolization procedures.

Synthesis published new progress about 27943-46-0. 27943-46-0 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Alkynyl,Ether, name is 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, and the molecular formula is C18H15N3O3, Recommanded Product: 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics

Christian, Alec H. published the artcileUncovering Subtle Ligand Effects of Phosphines Using Gold(I) Catalysis, Recommanded Product: 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, the publication is ACS Catalysis (2017), 7(6), 3973-3978, database is CAplus and MEDLINE.

Herein, we report the integration of simple linear regressions with gold(I) catalysis to interrogate the influence of phosphine structure on metal-catalyzed organic transformations. We demonstrate that observed product ratios in [4 + 3]/[4 + 2] cycloisomerization processes are influenced by both steric and electronic properties of the phosphine, which can be represented by the Au-Cl distance. In contrast, the observed selectivity of a similar [2 + 3]/[2 + 2] cycloisomerization is governed by L/B1, a steric parameter. Using this correlation, we were able to accurately predict the selectivity of a previously untested, Buchwald-type ligand to enhance selectivity for the same transformation. This ligand found further utility in increasing the selectivity of a previously reported gold-catalyzed cycloisomerization/arylation of 1,6-enynes by ∼1 kcal/mol.

ACS Catalysis published new progress about 27943-46-0. 27943-46-0 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Alkynyl,Ether, name is 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, and the molecular formula is C10H16O2, Recommanded Product: 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics