Analyzing the synthesis route of 125995-03-1

As the paragraph descriping shows that 125995-03-1 is playing an increasingly important role.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.125995-03-1,Atorvastatin lactone,as a common compound, the synthetic route is as follows.

Example 14 ; (2R,4R)-1-{2-[4-(tert-Butyldimethylsilyloxy)-6-oxotetrahydro-2-pyranyl]-ethyl}-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide; (23) (synthesis from Atorvastatin) was prepared in 92% yield according to WO 2005/012246 A1. [Show Image] LC-MS (ESI+) m/z 655 (M+1)., 125995-03-1

As the paragraph descriping shows that 125995-03-1 is playing an increasingly important role.

Reference£º
Patent; Ratiopharm GmbH; EP1834944; (2007); A1;,
Tetrahydropyran – Wikipedia
Tetrahydropyran – an overview | ScienceDirect Topics